So today I had a bit of a scare. I went to sync my iPhone 3G with my Macbook and noticed when I'd plug in the phone it would say it is syncing while iTunes simply showed nothing -- no kind of response whatsoever. Yes, everything is up to date on my Macbook so that was not the problem. After a few reboots of the Macbook and iPhone the same behavior still continued like clockwork.
Next step was to do some research online and send off an email to Rene for some more ideas. To our surprise this seems to be a bigger than we thought with many people seeing the same issue. I decided it could not hurt to give Apple a call about this and as I was on hold I figured I'd try one more time and shockingly it worked. I had to do a double take at my screens but it worked. To make sure it was not a fluke I unplugged everything and rebooted both Macbook and iPhone, still worked!
This issue seems to be completely random and Apple claims to be looking into it. So, if this happens to you, keep trying to sync, chances are you may get lucky. I'd say avoid doing a complete restore to your phone because if it does lock up during the restore you will be left with a empty iPhone. That's not good.
Hope Apple updates iTunes fast to prevent this from happening to any of our readers. In the meantime, have any of you had this misfortune?
Let us know!
[Thanks to @Rene for the backup!]