With iOS 5 Apple has finally cut the cord with iTunes and you no long have to tether your iPhone, iPod touch, or iPad over USB to your Windows or Mac PC just to sync over your stuff. Of course, you can still tether if you so wish, and it's just become part of your routine. However, you can also use iTunes Wi-Fi Sync so your device automatically transfers over content whenever you plug it in and are on the same Wi-Fi network as your desktop iTunes machine (i.e., when you put it on to charge at night.) Apple also has iCloud now, which
syncs stores and pushes not from your desktop but from Apple's giant data centers to all of your devices.
Have you gone (or stayed) all in on any one approach? Do you mix and match, for example use iCloud for personal information but still connect to iTunes for big files like movies? If you have a family and are managing iPhones, iPod touches, and iPads for spouses and kids, do you sync them all the same or does it vary? Do your kids games pop up on your work iPhone thanks to automatic downloads, or do their iPods get stale because it's become too much of a chore to keep everyone updated?
How is sync working for you in iOS 5? Does it "just work" or is it more complicated and confusing now than ever? Vote in the poll up top and let me know the details in the comments!