Apple has posted a support document to help those users (including many of those here at TiPb) who have been experiencing the dreaded BSOD (blue screen of death) when hooking up an iPhone or iPod to iTunes 8.
The solution? Uninstall iTunes and the MobileMe control panel, and reinstall the new version. Seems most people being affected have HP peripherals or Logitech drivers. I have neither, and my Vista install went fine, but if anyone did have the problem, please let us know if that fixed it!
Meanwhile, a couple of us here at TiPb have noticed that, apres-2.1, our MobileMe email is decidedly less pushy. We're deleting and recreating the account on our iPhone's, but no joy so far.