Apple has updated iTunes to version 12.4.1 This is a small update that fixes some issues with VoiceOver along with fixing some other bugs.

iTunes

Here's what's been fixed in iTunes 12.4.1:

  • This update addresses a number of problems where iTunes doesn't work as expected with VoiceOver. It also restores the option to Reset Plays and fixes the following issues:
  • Up Next may have unexpectedly played songs added together in the incorrect order.
  • iTunes was prevented from crossfading between songs.

You can download iTunes 12.4.1 from the Updates section of the Mac App Store.