iTunes App Store begins accepting iOS 4-compatible apps for review

Apple has sent out a notice to developers advising them that the iTunes App Store has begun accepting iOS 4 binaries for submission and review:
Submit your iOS 4 apps for review so they can be ready for sale when iOS 4 is available to iPhone and iPod touch users. Make sure you have built and tested your applications using iOS 4 and iPhone SDK 4 GM seed, which you can download from the iPhone Dev Center.Log in to iTunes Connect and upload your iOS 4 applications today.
iOS 4 is scheduled for release on June 21, once again developers aren't likely to get much sleep, especially if trying to once again implement new features for a device they don't have and can't yet test.
(The effort is much appreciated.)
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Rene Ritchie is one of the most respected Apple analysts in the business, reaching a combined audience of over 40 million readers a month. His YouTube channel, Vector, has over 90 thousand subscribers and 14 million views and his podcasts, including Debug, have been downloaded over 20 million times. He also regularly co-hosts MacBreak Weekly for the TWiT network and co-hosted CES Live! and Talk Mobile. Based in Montreal, Rene is a former director of product marketing, web developer, and graphic designer. He's authored several books and appeared on numerous television and radio segments to discuss Apple and the technology industry. When not working, he likes to cook, grapple, and spend time with his friends and family.