Seems iTunes 8 for Vista 32/64 will crash if you hook an iPhone or iPod up to it, or, you know, look at it funny. Gizmodo says some users are having luck reverting back to 7.7, or doing a complete uninstall and then installing 8.0. Apple, meanwhile, is asking for crash logs to try to figure out what's happening.
Could Apple's Quality Assurance department really not have any Vista machines in-house to run tests on? Any other company, and we wouldn't even ask but as reader Bryan points out in the comments: