Amazon has announced Kindle Editions with Audio/Video and it looks like the only way you can get it right now is on iPhone and iPad. Kindle Editions with Audio/Video:
allows readers to enjoy the benefits of embedded video and audio clips in Kindle books. The first books to take advantage of this new technology, including Rick Steves' London by Rick Steves and Together We Cannot Fail by Terry Golway, are available in the Kindle Store
"In the new Kindle Edition with audio/video of Rick Steves' London, the embedded walking tours allow customers to listen to Rick as they explore the sites of London," said Bill Newlin, publisher, Avalon Travel. "Rick's narration adds depth to the reader's experience, while listeners can follow the routes more easily with the text."
The Kindle app has also been updated to support iPhone 4's Retina Display. If you decide to try out these new fangled talking, walking eBooks, let us know what you think.